' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 4 Researches
8
USERS' SCORE
Very Good
Based on 2 Reviews
7.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
†
Rutin Powder (from Sophora japonica Flower Bud)
25 mg
†
Top Medical Research Studies
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
Study significantly highlights vitamin C’s role
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
Moderate relevance to topic.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
9
Vitamin C may lower blood pressure
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
Moderate relevance to cardiovascular research.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
Most Useful Reviews
7
Supports cardiovascular health
This quantity is substantial as I consumed a lot and bought this much. There are no issues with the ingredients and quality; they are consistent, and the effect is satisfactory. Some inflammations were alleviated. Vitamin C is a water-soluble vitamin, crucial for decomposing skin melanin, thus preventing pigmentation and treating melasma. It assists with collagen synthesis, promotes wound healing, and helps with cardiovascular disease.
Read More
8.8
Immunity improvement
This excellent high-dose vitamin C is essential for immunity against colds. I took it at the first signs of a cold, and it helped clear the infection quickly. During a more severe cold, it alleviated symptoms and shortened the illness duration. Though the capsules are large and can upset my sensitive stomach, this brand is preferable to pharmacy options. Sharing the capsules also helped my brother recover from his cold.
Read More
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Medical Researches
SCIENTIFIC SCORE
Most Likely Effective
Based on 4 Researches
8
9
Vitamin C may lower blood pressure
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
Moderate relevance to cardiovascular research.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
8
Antioxidants show promise for FGR
The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.
Lower relevance due to context
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Read More
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
Moderate relevance to topic.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
Study significantly highlights vitamin C’s role
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
User Reviews
USERS' SCORE
Very Good
Based on 2 Reviews
7.8
8.8
Immunity improvement
This excellent high-dose vitamin C is essential for immunity against colds. I took it at the first signs of a cold, and it helped clear the infection quickly. During a more severe cold, it alleviated symptoms and shortened the illness duration. Though the capsules are large and can upset my sensitive stomach, this brand is preferable to pharmacy options. Sharing the capsules also helped my brother recover from his cold.
Read More
7
Supports cardiovascular health
This quantity is substantial as I consumed a lot and bought this much. There are no issues with the ingredients and quality; they are consistent, and the effect is satisfactory. Some inflammations were alleviated. Vitamin C is a water-soluble vitamin, crucial for decomposing skin melanin, thus preventing pigmentation and treating melasma. It assists with collagen synthesis, promotes wound healing, and helps with cardiovascular disease.
Read More
